Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as The following sections contain reference sequences that belong to a Location: 1046 → 1232 Period_C Period protein 2/3C-terminal region PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. Location: 333 → 434 PAS PAS domain PAS motifs appear in archaea, eubacteria and eukarya. See identical proteins and their annotated locations for NP_073728.1 NG_012146.1 RefSeqGene Range 4957.49523 Download GenBank, FASTA, Sequence Viewer (Graphics) This section to the one reported in Genomic regions, Identify version mismatches by comparing the version of the RefSeq in These reference sequences are curated independently of the genomeĪnnotation cycle, so their versions may not match the RefSeq versions in the current These reference sequences exist independently of genome builds. Expression Ubiquitous expression in testis (RPKM 8.7), gall bladder (RPKM 7.6) and 25 other tissues See more Orthologs mouse all NEW Try the new Gene table Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Full Name period circadian regulator 2 provided by HGNC Primary source HGNC:HGNC:8846 See related Ensembl:ENSG00000132326 MIM:603426 AllianceGenome:HGNC:8846 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo Also known as FASPS FASPS1 Summary This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain.
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